放射性同位元素の臨床利用の研究

英文

• Oyama N, Ito H, Aoki Y, Miwa Y, Akino H, Kudo T, Okazawa H, Fujibayashi Y, Welch M, Yokoyama O: Carbon-11-acetate positron emission tomography (PET), versus fluorine- 18 fluorodeoxyglucose PET and CT for the diagnosis of recurrent prostate cancer after radical prostatectomy in cases of prostate specific antigen of more than 1 to 3ng/mL. Hell J Nucl Med 16 (2): 146-147, 2013
• Nanashima A, Abo T, Tobinaga S, Murakami G, Kido Y, Fukuda T, Tsuchiya T, Matsumoto H, Nagayasu T, Kudo T: Correlation between morphological and functional liver volume in each sector using integrated SPECT/CT imaging by computed tomography and technetium-99m galactosyl serum albumin scintigraphy in patients with various diseases who had undergone hepatectomy. Nucl Med Commun 34 (7): 652-659, 2013
• Nanashima A, Abo T, Murakami G, Matsumoto A, Tou K, Takeshita H, Kunizaki M, Hidaka S, Sakamoto I, Hayashi H, Fukuda T, Kudo T, Nagayasu T: Intrahepatic cholangiocarcinoma: relationship between tumor imaging enhancement by measuring attenuation and clinicopathologic characteristics. Abdom Imaging 38 (4): 785-792, 2013
• Nanashima A, Abo T, Kudo T, Sakamoto I, Hayashi H, Murakami G, Takeshita H, Hidaka S, Kido Y, Nagayasu T: Usefulness of examining hepatic functional volume using technetium-99m galactosyl serum albumin scintigraphy in hepatocellular carcinoma. Nucl Med Commun 3 4(5): 478-488, 2013
• Nanashima A, Abo T, Arai J, Matsumoto H, Kudo T, Nagayasu T. Functional liver reserve parameters predictive for posthepatectomy complications. J Surg Res 185 (1):127-135, 2013
• Koike H, Sueyoshi E, Kido Y, Nagayama H, Sakamoto I, Uetani M, Kudo T, Ikeda S: Pulmonary artery hypertension associated with systemic scleroderma: correlation among lung pulmonary blood volume, lung perfusion single photon emission computed tomography, and chest computed tomography images. Circulation 12 7(1): 141-142, 2013
• Fukuoka Y, Nakano A, Uzui H, Amaya N, Ishida K, Arakawa K, Kudo T, Okazawa H, Ueda T, Lee JD, Tada H: Reverse blood flow-glucose metabolism mismatch indicates preserved oxygen metabolism in patients with revascularised myocardial infarction. Eur J Nucl Med Mol Imaging 40 (8): 1155-1162, 2013
• Kudo T, Ideguchi R, Koide Y, Maemura K, Uetani M. Inter-operator agreement of functional parameter between medical student and professional nuclear cardiologist measured with newly developed freely available myocardial gated SPECT analysis program (Heart Function View). J Nucl Med 55 (s1): 1716, 2014
• Oyama N, Ito H, Takahara N, Miwa Y, Akino H, Kudo T, Okazawa H, Fujibayashi Y, Komatsu K, Tsukahara K, Yokoyama O. Diagnosis of complex renal cystic masses and solid renal lesions using PET imaging: comparison of 11C-acetate and 18F-FDG PET imaging. Clin Nucl Med 39 (3): e208-14, 2014
• Koike H, Sueyoshi E, Nagayama H, Ashizawa K, Sakamoto I, Uetani M, Kudo T, Ikeda S. Discrepancy between dual-energy computed tomography lung perfusion blood volume and lung perfusion single-photon emission computed tomography/computed tomography images in pulmonary embolism. Am J Respir Crit Care Med 189 (12): e71-2, 2014
• Kudo T, Ideguchi R, Uetani M, Nanashima A, Nagayasu T: Delayed FDG image obtained 90 min after injection gives incremental information which correlates histopathological data; Analysis with surgically resected pancreatic cancer. Eur J Nucl Med Mol Imaging 42 (suppl 1) S650
• Kudo T, Ideguchi R, Uetani M, Koide Y, Maemura K: Interchangeability of cardiac volumetric and phase analysis parameters between two software (CardioRepo and Heart Function View). Eur J Nucl Med Mol Imaging 42 (suppl 1) S506
• Kudo T. Ideguchi R. The Effects of Medical Radiation: A Few Things Nuclear Cardiologists Must Know. Ann Nucl Cardiol 1 (1): 35-42, 2015
• Ideguchi R, Ashizawa K, Akashi S, Shindo M, Minami K, Fukuda T, Irie J, Fukuda M, Uetani M: Malignant Pleural Mesothelioma with Marked Lymphatic Involvement: A Report Of Two Autopsy Cases. Case Rep Oncol Med. doi: 10.1155/2017/6195898, 2017
• Misaka T, Hosono M, Kudo T, Ito T, Syomura T, Uemura M, Okajima K: Influence of acquisition orbit on phase analysis of gated single photon emission computed tomography myocardial perfusion imaging for assessment of left ventricular mechanical dyssynchrony. Ann Nucl Med. 31(3): 235-244, 2017
• Nakajima K, Kudo T, Nakata T, Kiso K, Kasai T, Taniguchi Y, Matsuo S, Momose M, Nakagawa M, Sarai M, Hida S, Tanaka H, Yokoyama K, Okuda K: Edenbrandt L: Diagnostic accuracy of an artificial neural network compared with statistical quantitation of myocardial perfusion images: a Japanese multicenter study. Eur J Nucl Med Mol Imaging. 44(13): 2280-2289, 2017
• Kudo T, Yoshinaga K, Takeishi Y, Nakajima K. Statement on 18F-FDG PET Usage for Large-vessel Vasculitis. Annals of Nuclear Cardiology. 4: 46-51, 2018
• Myssayev A, Ideguchi R, Chiba A, Koide Y, Uetani M, Maemura K, Kudo T. Can Stress-induced Phase Change be Observed on 99mTc Pharmacological Stress Myocardial Perfusion Imaging? Annals of Nuclear Cardiology. 4: 34-41, 2018
• Myssayev A, Myssayev A, Ideguchi R, Eguchi S, Adachi T, Sumida Y, Tobinaga S, Uetani M, Kudo T　Usefulness of FDG PET/CT derived parameters in prediction of histopathological finding during the surgery in patients with pancreatic adenocarcinoma. PloS one 14(1) : e0210178, 2019
• Chen X, Kudo T, Lapa C, Buck A, Higuchi T: Recent advances in radiotracers targeting norepinephrine transporter: structural development and radiolabeling improvements J Neural Transm (Vienna) 127(6): 851-873, 2020
• Kamasaki T, Mori K, Taira Y, Orita M, Miyamoto I, Usui T, Chiba K, Kudo T, Takamura N.: PET/computed tomography shows association between subjective pain in knee joints and fluorine-18-fluorodeoxyglucose uptake. Nucl Med Commun. 41(3): 241-245, 2020
• Kawano H, Kudo T, Maemura K.: (123)I-β-Methyl Iodophenyl Pentadecanoic Acid and (201)Thallium Dual Myocardial Single-Photon Emission Computed Tomography (BMIPP/Tl SPECT) Detection of Myocardial Damage of Systemic Sclerosis. Circ J. 8(10): 1886, 2020
• Kudo T, Imakhanova A.: Quantification of amyloid deposition using bone scan agents. J Nucl Cardiol epub: 2020
• Kudo T, Inano A, Midorikawa S, Kubo H, Hayashi K, Nakashima S, Fukushima C, Maeda K, Oriuchi N, Irie S, Yamashita S, Kusuhara H.: Determination of the Kinetic Parameters for 123I Uptake by the Thyroid, Thyroid Weights, and Thyroid Volumes in Present-day Healthy Japanese Volunteers. Health Phys 118(4): 417-426, 2020
• Matsukawa K, Arimura T, Orita M, Kondo H, Chuman I, Ogino T, Taira Y, Kudo T, Takamura N.: Health-related quality of life in Japanese patients with prostate cancer following proton beam therapy: an institutional cohort study. Jpn J Clin Oncol. 50(5): 519-527, 2020
• Ikebe Y, Ishimaru H, Imai H, Abe K, Izumo T, Morofuji Y, Ideguchi R, Morikawa M, Uetani M. : Quantitative Susceptibility Mapping for Carotid Atherosclerotic Plaques: A Pilot Study. Magnetic resonance in medical sciences 1(19): 135-140, 2020
• Sasaki, M., Hotokezaka, Y., Ideguchi, R., Uetani, M., Fujita, S: Traumatic myositis ossificans: multifocal lesions suggesting malignancy on FDG-PET/CT—a case report.  Skeletal Radiology, 50(1): 249-254, 2020
• Kawano H, Kudo T, Maemura K.: Myocardial Metabolic Abnormality in a Patient With Uremic Cardiomyopathy. Circ J. 85(10): 1895,2021.
• Hirschfeld CB, Shaw LJ, Williams MC, Lahey R, Villines TC, Dorbala S, Choi AD, Shah NR, Kudo T, et al: Impact of COVID-19 on Cardiovascular Testing in the United States Versus the Rest of the World. JACC Cardiovasc Imaging 14(9): 1787-1799,2021.
• Tsuji S, Iwamoto N, Horai Y, Fujikawa K, Fujita Y, Fukui S, Ideguchi R, Michitsuji T, et al.: Comparison of the quantitative measurement of 18F-FDG PET/CT and histopathological findings in IgG4-related disease. Clinical and experimental rheumatology 39(6): 1338-1344,2021.
• Kawano H, Sakai K, Kudo T, Arakawa S, Doi Y, Takei A, Fukae S, Maemura K.: Sympathetic nerve abnormality in an adolescent patient with cardioinhibitory vasovagal syncope.. J Cardiol Cases. 24(5): 230-233,2021.
• Chiba A, Kudo T, Ideguchi R, Altay M, Koga S, Yonekura T, Tsuneto A, Morikawa M,et al.: Usefulness of an artificial neural network for a beginner to achieve similar interpretations to an expert when examining myocardial perfusion images. Int J Cardiovasc Imaging. Int J Cardiovasc Imaging 37(7): 2337-2343,2021.
• Kawano H, Kudo T, Umeda M, Futakuchi M, Sueyoshi E, Maemura K.: Myocardial Damage and Microvasculopathy in a Patient With Systemic Sclerosis. Circ J. 85(2): 224,2021.
• Einstein AJ, Shaw LJ, Hirschfeld C, Williams MC, Villines TC, Better N, Vitola JV, Cerci R, et al.: International Impact of COVID-19 on the Diagnosis of Heart Disease.. J Am Coll Cardiol. 77(2): 173-185,2021.
• Kubota K, Tanaka N, Miyata Y, Ohtsu H, Nakahara T, Sakamoto S, Kudo T, Nishiyama Y, et al.: Comparison of 18 F-FDG PET/CT and 67 Ga-SPECT for the diagnosis of fever of unknown origin: a multicenter prospective study in Japan. Ann Nucl Med. 35(1): 31-46,2021.
• Kudo T, Nessipkhan AE.: Modalities for predicting events in patients with ICDs: Expanding the versatility of FDG PET. J Nucl Cardiol. 28(2): 478-480,2021.
• Kudo T, Lahey R, Hirschfeld CB, Williams MC, Lu B, Alasnag M, Bhatia M, Bom H-SH,et al. on behalf of INCAPS COVID Investigators Group.: Impact of COVID-19 Pandemic on Cardiovascular Testing in Asia: The IAEA INCAPS-COVID Study. JACC: Asia 1(2): 187-199,2021.
• Oki N, Ikebe Y, Koike H, Ideguchi R, Niino D, Uetani M: FDG-PET vs. chemical shift MR imaging in differentiating intertrabecular metastasis from hematopoietic bone marrow hyperplasia. Japanese Journal of Radiology 39(11): 1077-1085,2021.

邦文

• 工藤崇：特集「心臓核医学の最前線（前編）」２）心筋代謝とPET薬剤． PETジャーナル23(3)：34-36, 2013
• 井手口怜子，工藤 崇，上谷雅孝：心機能評価におけるCardioRepoの有用性　核医学 S267, 2014
• 工藤 崇，井手口怜子，上谷雅孝：Heart Function View vs. CardioRepo: 位相解析の対比　核医学 S259, 2014
• 西 弘大： 物理系薬学Topics 「放射性アミノ酸アナログ：Anti-18F-FACBCはFDGを超えるか？」. 日本薬学会誌ファルマシア 50 (6): 571, 2014
• 井手口怜子, 工藤 崇, 上谷雅孝：位相解析の虚血性心疾患に対する付加価値は薬物付加でも認められるか？：CardioRepoとHFVを用いての検討. 核医学52(3), S280, 2015
• 工藤 崇：Heart Risk Vier-F, Heart Risk View-Sの使用経験：解析例の紹介と臨床での活用について. 核医学52(3), S106, 2015
• 井手口怜子：脳のMRI Chapter14神経皮膚症候群（メディカルサイエンス・インターナショナル）912-915 & 191-925, 2015
• 井手口怜子：脳疾患に対するASL(artery spin lableling)の有用性—急性脳症を中心に−　臨床放射線 60(5):621-631,2015
• 井手口怜子：連載　画像から読み解く感染症（２）I中枢神経　２.トキソプラズマ症　化学療法の領域 31(8):4-11,2015
• 工藤 崇、井手口怜子、角田順久、永安 武、福岡順也、上谷雅孝：膵癌におけるFDG-PETと病理組織の関係：後期撮影の意義. 核医学. 53 (Supplement): S315; 2016
• 井手口怜子、工藤 崇、上谷雅孝：蛋白漏出性胃腸症に対する蛋白漏出シンチの有用性. 核医学. 53 (Supplement): S271, 2016
• 河田宗一郎、伊藤 暢宏、北島　翼、舩越 康智、岡田 雅彦、井手口怜子、森内 浩幸： 画像診断で脳腫瘍との鑑別に苦慮した多発性脳膿瘍．日本小児科学会雑誌. 120 (1): 43-48; 2016
• 井手口怜子、上谷雅孝：脳梗塞の画像診断．長崎市医師会報 第608号, p29-33, 2017
• 井手口怜子、松尾孝之、石丸英樹：下垂体神経膠腫 (pituitary glioma)．下垂体の画像診断　MEDICAL VIEW, p151-154, 2017
• 工藤　崇：国際委員会報告・ASNC2017に参加して. 日本心臓核医学会誌 Vol.20-1, p31, 2017
• 工藤　崇、ミセイエフ アルタイ、井手口 怜子：膵癌におけるFDG-PETと病理所見の関係 : 有用なFDG-PETパラメーターは何か．臨床照射線 62(8), p1071-1079, 2017
• 井手口怜子．小児脳神経疾患のASL（大場 洋 編集，小児科診療，診断と治療社，東京，8月号 p983-988所収）2018年．
• 工藤　崇：cardioREPOを用いた心臓核医学コンピューター支援診断. RadFan 19(6): 44-47, 2021.

放射線による医療被ばくと職業被ばく

英文

• Ideguchi R, Yoshida K, Ohtsuru A, Takamura N, Tsuchida T, Kimura H, Uetani M, Kudo T. The present state of radiation exposure from pediatric CT examinations in Japan-what do we have to do? J Radiat Res. 59 (suppl_2): ii130-ii136, 2018
• Karo C, Ideguchi R, Nishi K, Fukuda N, Miura M, Matuda N, Kudo T. Radiation Monitoring of an Isolation Room for 131I Therapy After the Patients Were Released. HealthPhys 117 (4) : p419 - 425, 2019

邦文

• 岡市協生, 土屋皓平, 古賀　哲, 江藤　良, 工藤　崇：放射線被曝によるマイクロRNAの誘導にはp53のリン酸化が関与する. 広島医学, 67巻, 330-332, 2014
• 岡市協生, 福田正和, 工藤　崇：低線量放射線によるマイクロRNAの誘導. 長崎医学会雑誌学, 89巻, 262-264, 2014
• 工藤　崇：医療と被ばく：正当化と最適化・医療被ばくと職業被ばく. 臨床核医学 54(3): 39-42, 2021.

学会発表

• 工藤 崇, 上谷雅孝, 木村浩彦, 土田達郎, 高村　昇, 吉田浩二, Lucian Krille, Steffen Mueller：Comparison of International and domestic pediatric CT usage.第73回日本医学放射線学会学術集会抄録集 s351, 2014

小動物PET/SPECT/CTによる前臨床分子イメージング

英文

• Kobayashi M, Nakanishi T, Nishi K, Higaki Y, Okudaira H, Ono M, Tsujiuchi T, Mizutani A, Nishii R, Tamai I, Arano Y, Kawai K. Transport Mechanisms of Hepatic Uptake and Bile Excretion in Clinical Hepatobiliary Scintigraphy with 99mTc-N-pyridoxyl-5-methyltryptophan. Nucl Med Biol 41 (4): 338-342, 2014
• Matsunari I, Miyazaki Y, Kobayashi M, Nishi K, Mizutani A, Kawai K, Hayashi A, Komatsu R, Yonezawa S, Kinuya S. Performance evaluation of the eXplore speCZT preclinical imaging system. Ann Nucl Med 28 (5): 484-497, 2014
• Mizutani A, Matsunari I, Kobayashi M, Nishi K, Fujita W, Miyazaki Y, Nekolla SG, Keiichi Kawai: Impact of injection dose, post-reconstruction filtering, and collimator choice on image quality of myocardial perfusion SPECT using cadmium-zinc telluride detectors in the rat. EJNMMI Phys. Dec; 2(1): 7, 2015
• Nishi K, Mizutani A, Shikano N, Fujita K, Kobayashi M, Ono M, Nishii R, Sasaki Y, Kinuya S, Kawai K: In vivo radioactive metabolite analysis for individualized medicine: A basic study of a new method of CYP activity assay using 123I-IMP. Nucl Med Biol. 42(2): 171-176; 2015
• Mizuta S, Otaki H, Kitamura K, Nishi K, Watanabe K, Makau JN, Hashimoto R, Usui T, Chiba K: 3,3-Dibromo-2-trifluoromethyl Acrylic Acid Ethyl Ester: A Versatile Platform for the Stereoselective Preparation of Functionalized- α-Trifluoromethyl α,β-Unsaturated Lactones and Trifluoromethyl Pyrazolinones. Org. Chem. Front. 2016. 3, 1661-1667; 2016
• Mizuta S, Kitamura K, Nishi K, Hashimoto R, Usui T, Chiba K: Activity of N,N’-dialkyl-2-trifluoromethyl-thioimidazolium salts as phase- transfer catalyst for the alkylation of active methylene compounds. RSC Adv. 6:43159-43162; 2016
• Kobayashi M, Matsunari I, Nishi K, Mizutani A, Miyazaki Y, Ogai K, Sugama J, Shiba K, Kawai K, Kinuya S: Simultaneous acquisition of 99mTc and 123I-labeled radiotracers using a preclinical SPECT scanner with CZT detector. Ann Nucl Med. 30(4):263-71; 2016
• Shimada S, Aoki K, Nabeshima T, Fuxun Y, Kurosaki Y, Shiogama K, Onouchi T, Sakaguchi M, Fuchigami T, Ono H, Nishi K, Posadas-Herrera G, Uchida L, Takamatsu Y, Yasuda J, Tsutsumi Y, Fujita H, Morita K, Hayasaka D: Tofla virus: A newly identified Nairovirus of the Crimean-Congo hemorrhagic fever group isolated from ticks in Japan. Sci Rep 6:20213; 2016
• Hayasaka D, Nishi K, Fuchigami T, Shiogama K, Onouchi T, Shimada S, Tsutsumi Y, Morita K: 18F-FDG PET imaging for identifying the dynamics of intestinal disease caused by SFTSV infection in a mouse model. Oncotarget. 7 (1):140-147; 2016
• Fuchigami T, Ono H, Oyadomari K, Iwatake M, Hayasaka D, Akbari M, Yui K, Nishi K, Kudo T, Yoshida S, Haratake M, Nakayama M: Development of a 68Ge/68Ga generator system using polysaccharide polymers and its application in PET imaging of tropical infectious diseases. ACS Omega 2(4): 1400-1407, 2017
• Mizuta S, Otaki H, Kitagawa A, Kitamura K, Morii Y, Ishihara J, Nishi K, Hashimoto R, Usui T, Chiba K: Ionic Liquid-Mediated Hydrofluorination of o-Azaxylylenes Derived from 3-Bromooxindoles. Org Lett. 19(10): 2572-2575, 2017
• Kobayashi M, Mizutani A, Nishi K, Nakajima S, Shikano N, Nishii R, Fukuchi K, Kawai K: Difference in accumulation and the transport mechanism of L- and D-methionine in high- and low-grade human glioma cells. Nucl Med Biol, 14(44): 78-82, 2017
• Luo L, Tang J, Nishi K, Yan C, Dinh PU, Cores J, Kudo T, Zhang J, Li TS, Cheng K: Fabrication of Synthetic Mesenchymal Stem Cells for the Treatment of Acute Myocardial Infarction in Mice. Circ Res. 120(11): 1768-1775, 2017
• Luo L, Nishi K, Urata Y, Yan C, Hasan AS, Goto S, Kudo T, Li ZL, Li TS: Ionizing radiation impairs endogenous regeneration of infarcted heart: an in vivo 18F-FDG PET/CT and 99mTc-tetrofosmin SPECT/CT study in mice. Radiation Res. 187(1): 89-97, 2017.
• Wen JZ, Kobayashi M, Yamada K, Nishi K, Takahashi K, Mizutani A, Nishii R, Flores LG 2nd, Shikano N, Kunishima M, Kawai K. Development of radioiodine-labeled acetaminophen for specific, high-contrast imaging of malignant melanoma. Nucl Med Biol. 59:16-21, 2018.
• Mizutani A, Kobayashi M, Fujita K, Takahashi K, Hokama T, Takasu H, Nishi K, Nishii R, Shikano N, Fukuchi K, Kawai K. 123I-iomazenil whole-body imaging to detect hepatic carboxylesterase drug-metabolizing enzyme activity. Nucl Med Commun. 39(9): 825-833, 2018.
• Kobayashi M, Tsujiuchi T, Okui Y, Mizutani A, Nishi K, Nakanishi T, Nishii R, Fukuchi K, Tamai I, Kawai K. Different Efflux Transporter Affinity and Metabolism of 99mTc-2-Methoxyisobutylisonitrile and 99mTc-Tetrofosmin for Multidrug Resistance Monitoring in Cancer. Pharm Res. 36(1): 18, 2018.
• Kobayashi M, Kato T, Washiyama K, Ihara M, Mizutani A, Nishi K, Flores LG 2nd, Nishii R, Kawai K. The pharmacological properties of 3-arm or 4-arm DOTA constructs for conjugation to α-melanocyte-stimulating hormone analogues for melanoma imaging. PloS one 14(3) : e0213397, 2019
• Mizuta S, Makau JN, Kitagawa A, Kitamura K, Otaki H, Nishi K, Watanabe K. Synthesis of Trifluoromethyl-α,β-unsaturated Lactones and Pyrazolinones and Discovery of Influenza Virus Polymerase Inhibitors. ChemMedChem 13 (22) : 2390 - 2399, 2019
• Kobayashi M, Nishi K, Mizutani A, Hokama T, Matsue M, Tsujikawa T, Nakanishi T, Nishii R, Tamai I, Kawai K Imaging of hepatic drug transporters with 131I 6-β-iodomethyl-19-norcholesterol. Scientific reports 9 (1) : 13413, 2019
• Yoshida M, Tashiro M, Nishi K, Mishima M, Kawano K, Takazono T, Saijo T, Yamamoto K, Imamura Y, Miyazaki T, Kudo T, Yanagihara K, Mukae H and Izumikawa K: Detection of invasive pulmonary aspergillosis in mice using lung perfusion single-photon emission computed tomography with [99mTc]MAA. Med Mycol. 58(7): 965-972, 2020
• Kobayashi M, Nishi K, Mizutani A, Okudaira H, Nakanishi T, Shikano N, Nishii R, Tamai I, Kawai K: Transport mechanism and affinity of [99mTc]mercaptoacetyltriglycine ([99mTc]MAG3) on the apical membrane of renal proximal tubule cells. Nucl Med Biol 84-85: 33-37, 2020
• Fuchigami T, Kawasaki M, Watanabe H, Nakagaki T, Nishi K, Sano K, Atarashi R, Nakaie M, Yoshida S, Ono M, Nishida N, Nakayama M: Feasibility studies of radioiodinated pyridyl benzofuran derivatives as potential SPECT imaging agents for prion deposits in the brain. Nucl Med Biol 90-91: 41-48, 2020
• Kobayashi M, Mizutani A, Nishi K, Muranaka Y, Nishii R, Shikano N, Nakanishi T, Tamai I, Kleinerman ES, Kawai K.: [131I]MIBG exports via MRP transporters and inhibition of the MRP transporters improves accumulation of [131I]MIBG in neuroblastoma. Nucl Med Biol 90-91: 49-54, 2020
• Nishi K, Kudo T. : Chapter1-7 PET/CT for Inflammatory Diseases-Basic Science, Typical Cases, and Review : 34-37, 2020 .
• Nishi K, Kobayashi M, Kikuchi M, Mizutani A, Muranaka Y, Tamai I, Kawai K, Kudo T.: Inhibition of the Hepatic Uptake of (99m)Tc-Tetrofosmin Using an Organic Cation Transporter Blocker. Pharmaceutics 13(7): 1073,2021.
• Kinoshita T, Watanabe K, Sakurai Y, Nishi K, Yoshikawa R, Yasuda J: Co-infection of SARS-CoV-2 and influenza virus causes more severe and prolonged pneumonia in hamsters. Scientific reports 11(1): 21259,2021.
• Kobayashi M, Mizutani A, OkamotoT, Muranaka Y, Nishi K, Nishii R, Shikano N, Nakanishi T, Tamai I, Eugenie SK, Kawai K: Assessment of drug transporters involved in the urinary secretion of [99mTc]dimercaptosuccinic acid. Nuclear Medicine and Biology 94-95: 92-97,2021.

邦文

• 西 弘大、松田尚樹、三浦美和、林田りか、山内基弘、平川美弥子、高尾秀明、工藤 崇：小動物分子イメージングの放射線施設への導入効果．日本放射線安全管理学会誌. 15 (1): 74-79; 2016
• 西 弘大．教育講座－放射線後術学を用いた先端生命科学研究－ 第10回「前臨床核医学の基礎と病態への応用」日本放射線技術学会雑誌 74巻10号 p1207-1211.

学会発表

• 西 弘大, 松田尚樹, 三浦美和, 林田りか, 山内基弘, 高尾秀明, 工藤 崇：小動物分子イメージングの放射線施設への導入効果. 日本放射線安全管理学会 第14回学術大会講演予稿集 p68 2015
• 高橋浩太郎, 水谷明日香, 佐野達哉, 外間つづみ, 西 弘大, 小林正和, 川井恵一：123I-IMP代謝物分析による臨床薬剤負荷時のCYP活性定量. 核医学S290, 2015
• 西 弘大, 三嶋麻揮, 田代将人, 吉田將孝, 池田英史, 泉川公一, 松田尚樹, 工藤 崇：浸潤性肺アスペルギルス症に対する肺血流SPECTの有用性の検討. 核医学52(3), S303, 2015
• 小林正和、水谷明日香、松成一朗、西 弘大、宮崎吉春、柴 和弘、川井恵一：CZT半導体検出器を搭載した小動物SPECTイメージングにおける投与放射能、コリメータと平滑化フィルター処理の影響. JSMI Report 8(2): 147; 2015
• 西 弘大、田代将人、吉田將孝、池田英史、三嶋麻揮、泉川公一、松田尚樹、工藤 崇：肺血流SPECTによるアスペルギルス感染マウスの経過観察.　JSMI Report 8(2): 169; 2015
• 三嶋麻揮、西 弘大、田代将人、辻野耕平、河野 圭、吉田將孝、松田尚樹、工藤 崇、泉川公一：Dynamic Imaging によるIPAモデルマウスにおける肺血流動態解析. 核医学. 53 (Supplement): S310, 2016
• 稲川耕平、丹羽隆博、西 弘大、小林正和、川井恵一：脳腫瘍細胞におけるD-methionineの集積生と集積機序の検討. 核医学. 53 (Supplement): S265, 2016
• 羅　蘭、西 弘大、Chen Y、浦田芳重、工藤 崇、李　桃生：放射線被ばくによる心血管疾患リスクに関する実験的評価. 第57回原子爆弾後障害研究会講演抄録p30
• 小林正和、水谷明日香、辻内孝文、西 弘大、福地一樹、川井恵一：99mTc放射性医薬品における腫瘍細胞外排泄機序の違い. JSMI Report. 9 (2): p203, 2016
• 有薗ケイラ、西　弘大、佛坂斉祉、森田幸子、橋本　恵、近藤崇伸、井野愛理、有田光太郎、黒濱武士、吉田教明：小動物用SPECTを用いた矯正力による歯槽骨の骨代謝変化の経過観察. 核医学57(Supplement), S208, 2017
• 西　弘大、小林正和、目代佑太朗、辻野耕平、川井恵一、工藤　崇：99mTc-tetrofosminの肝集積機序と輸送阻害効果. 核医学57(Supplement), S183, 2017
• 西　弘大、松田尚樹、工藤　崇：小動物分子イメージングの新領域への展開と応用.日本放射線安全管理学会第16回学術大会要旨集, p119, 2017
• 目代佑太朗、西　弘大、小林正和、辻野耕平、川井恵一、工藤　崇：99mTc-tetrofosminの肝集積メカニズムと肝集積阻害効果の検証. JSMI Report. 10(2), p154, 2017
• 西 弘大，松田尚樹，工藤 崇．前臨床分子イメージングエリアの室内放射線環境モニタリングの試み．日本放射線安全管理学会 第17回学術大会予稿集p34，2018年．

精密型ホールボディーカウンター（WBC）による体内放射能の測定

英文

• Matsuda N, Yoshida K, Nakashima K, Iwatake S, Morita N, Ohba T, Yusa T, Kumagai A, Ohtsuru A: Initial activities of a radiation emergency medical assistance team to Fukushima from Nagasaki. Radiat Meas 55: 22-25, 2013
• Matsuda N, Morita N, Miura M, Yamauchi M, Kudo T, Usa T: Internal radioactivity of temporary residents in Fukushima within one year after the radiological accident. J Environ Occup Sci 2: 123-130, 2013
• Morita N, Miura M, Usa T, Kudo T, Matsuda N: Internal radiation doses in 372 persons who were dispatched to Fukushima from April 2011 to March 2012. Radiation Safety Management 12: 48-55, 2013
• Morita N, Miura M, Yoshida M, Kumagai A, Ohtsuru A, Usa T, Kudo T, Takamura N, Yamashita S, Matsuda N: Spatiotemporal characteristics of internal radiation exposure in evacuees and first responders after the radiological accident in fukushima. Radiat Res 180 (3): 299-306, 2013
• Matsuda N, Kumagai A, Ohtsuru A, Morita N, Miura M, Yoshida M, Kudo T, Takamura N, Yamashita S: Assessment of internal exposure doses in Fukushima by a whole body counter within one month after the nuclear power plant accident. Radiat Res 179 (6): 663-668, 2013

学会発表

• 福田直子：原子力防災における体外計測の経験の総括と課題. 日本保健物理学会第50回研究発表会日本放射線安全管理学会第16回学術大会 合同大会講演予稿集, p35, 2017

その他

英文

• Okaichi K, Izumi N, Takamura Y, Fukui S, Kudo T: Transcriptional specificity in various p53-mutant cells. Anticancer Res 33 (3): 923-928, 2013
• Ihara M, Takeshita S, Okaichi K, Okumura Y, Ohnishi T. Heat exposure enhances radiosensitivity by depressing DNA-PK kinase activity during double strand break repair. Int J Hyperthermia. 30 (2): 102-9, 2014
• Ihara M, Ashizawa K, Shichijo K, Kudo T. Expression of the DNA-dependent protein kinase catalytic subunit is associated with the radiosensitivity of human thyroid cancer cell lines. J Radiat Res. 60(2) p171 – 177, 2019
• Hori H, Orita M, Taira Y, Kudo T, Takamura N. Risk perceptions regarding radiation exposure among Japanese schoolteachers living around the Sendai Nuclear Power Plant after the Fukushima accident. PloS one 14 (3) : e0212917, 2019
• Matsunaga H, Orita M, Iyama K, Sato N, Aso S, Tateishi F, Taira Y, Kudo T, Yamashita S, Takamura N. Intention to return to the town of Tomioka in residents 7 years after the accident at Fukushima Daiichi Nuclear Power Station: a cross-sectional study. J Radiat Res. 60 (1) : p51 – 58, 2019
• Hori H, Orita M, Taira Y, Matsunaga H, Kudo T, Takamura N.: Factors affecting anxiety among administrative officers working within the urgent protective action planning zone of a nuclear power station. PLoS One 15(8): e0236997-0 2020
• Ihara M, Shichijo K, Ashizawa K, Matsuda K, Otsubo R, Horie I, Nakashima M, Kudo T. : Relationship between thyroid tumor radiosensitivity and nuclear localization of DNA-dependent protein kinase catalytic subunit J Radiat Res 61(4): 511, 2020 doi: 10.1093/jrr/rraa032. (IF: 2.724)
• Ihara M, Shichijo K, Takeshita S, Kudo T.: Wortmannin, a specific inhibitor of phosphatidylinositol-3-kinase, induces accumulation of DNA double-strand breaks. J Radiat Res 61(2): 171-176, 2020
• Matsunaga H, Orita M, Taira Y, Kudo T, Kondo H, Yamashita S, Takamura N.: Intention to Return and Perception of the Health Risk Due to Radiation Exposure Among Residents in Tomioka Town, Fukushima Prefecture, Stratified by Gender and Generation. Disaster Med Public Health Prep. ( ): 1-8, 2020

学会発表

• 齋藤裕一郎，井原 誠，平山亮一，下等晃弘，小林純也，小松賢志：レポーター遺伝子を用いた生存率曲線定量モデル"saturable Repair Model"の生物学的検証. 日本放射線影響学会第５６回大会　講演要旨集pp165, 2013
• 井原 誠，小林純也，栗政明弘，小松賢志，工藤 崇：Ｋｕ欠損細胞における相同組換え修復. 日本放射線影響学会第５６回大会　講演要旨集pp162, 2013
• 岡市協生，土屋皓平，古賀哲，江藤良，工藤 崇：放射線被曝によるマイクロRNAの誘導にはp53のリン酸化が関与する．第54回原爆後障害研究会 講演要旨集pp29, 2013
• 岡市協生，工藤 崇：p53のホットスポット変異によりARFとINK4A経路が抑制されて癌になりやすくなる．日本放射線影響学会第５６回大会　講演要旨集pp118, 2013
• 岡市協生, 福田正和, 工藤 崇：低線量放射線によるマイクロRNAの誘導. 第55回原爆後障害研究会講演要旨集, p17, 2014
• 井原 誠, 小林純也, 栗政明弘, 小松賢志, 工藤 崇：DNA-PK複合体サブユニット欠損細胞における修復系 第57回日本放射線影響学会講演要旨集, p149, 2014
• 岡市協生, 工藤 崇：マイクロRNAのmiR-34aはp53の脱リン酸により誘導される. 第57回日本放射線影響学会講演要旨集, p134, 2014
• 松田尚樹、山内基弘、西 弘大、久下裕司、久保直樹、渡部浩司、桧垣正吾、柴　和弘、柴田理尋、川本卓男、戸崎充男、角山雄一、小野俊朗、花房直志、中島　覚、稲田晋宣、松島亮人、杉原真司：放射線施設による緊急モニタリングプラットフォームの構築. 日本放射線安全管理学会 第15回学術大会講演予稿集p67, 2016
• 西 弘大、松田尚樹、山内基弘、折田真紀子、高村 昇、工藤 崇：看護師を対象とした放射線教育プログラムの新展開. 日本放射線安全管理学会 第15回学術大会講演予稿集p69, 2016