2024年
- Kim SE, Noda R, Liu YC, Nakajima Y, Kameoka S, Motooka D, Mizuno S, Takahashi S, Takaya K, Murase T, Ikematsu K, Tratsiakova K, Motoyama T, Nakashima M, Kishi K, Martin P, Seno S, Okuzaki D, Mori R.
Novel integrated multiomics analysis reveals a key role for integrin beta-like 1 in wound scarring.
EMBO Reports, PMID: 39558136. - Moriyama M, Mori R, Hayakawa T, Moriyama H.
FoxO3a Plays a Role in Wound Healing by Regulating Fibroblast Mitochondrial Dynamics.
Journal of Investigative Dermatology, PMID: 39547393. - Nakajima Y, Obata S, Takaya K, Sakai S, Suzuki Y, Okabe K, Aramaki-Hattori N, Mori R, Kadoya Y, Kishi K.
Tunneling nanotube-driven complete regeneration of murine fetal skin.
Scientific Reports, 14, 17215, 2024, PMID: 39060558.
2022年
- Umehara T, Mori R, Mace KA, Tanaka K, Sakamoto N, Ikematsu K, Sato H.
circRNAs may be involved in dysfunction of neutrophils of type 2 diabetic mice through regulation of specific miRNAs.
Biomedicines, 10, 3129, 2022, PMID: 36551885. - Umehara T, Mori R, Murase T, Tanaka T, Kasai K, Ikematsu K, Sato H.
rno-miR-203a-3p and Mex3B contribute to cell survival of iliopsoas muscle via the Socs3-Casp3 axis under severe hypothermia in rats.
Legal Medicine, 59, 102150, 2022, PMID: 36198254. - Sun L, Kim S, Mori R, Miyaji N, Nikawa T, Hirasaka K.
Astaxanthin Exerts Immunomodulatory Effect by Regulating SDH-HIF-1α Axis and Reprogramming Mitochondrial Metabolism in LPS-Stimulated RAW264.7 Cells.
Marine Drugs, 20, 660, 2022, PMID: 36354983. - Inamasu E, Tsuchiya T, Yamauchi M, Nishi K, Matsuda K, Sugawara F, Sakaguchi K, Mori R, Matsumoto K, Miyazaki T, Hatachi G, Doi R, Watanabe H, Tomoshige K, Matsuda N, Higami Y, Shimokawa I, Nakashima M, Nagayasu T.
Anticancer agent α-sulfoquinovosyl-acylpropanediol enhances the radiosensitivity of human malignant mesothelioma in nude mouse models,
Journal of Radiation Research, 63, 19-29, 2022, PMID: 34738103.
2021年
- Park S, Komatsu T, Hayashi H, Mori R, Shimokawa I.
The role of neuropeptide Y in adipocyte-macrophage crosstalk during high fat diet-induced adipose inflammation and liver steatosis,
Biomedicines, 9, 1739, 2021, PMID: 34829968. - Ishii M, Tsuchiya T, Doi R, Morofuji Y, Fujimoto T, Muto H, Suematsu T, Mori R, Matsumoto K, Miyazaki T, Tomoshige K, Watanabe H, Iwatake M, Nagayasu T.
Increased in vitro intercellular barrier function of lung epithelial cells using adipose-derived mesenchymal stem/stromal cells,
Pharmaceutics, 13, 1264, 2021, PMID: 34452225. - Kinoshita A, Ohyama K, Tanimura S, Matsuda K, Kishino T, Negishi Y, Asahina N, Shiraishi H, Hosoki K, Tomiwa K, Ishihara N, Mishima H, Mori R, Nakashima M, Saitoh S, Yoshiura KI.
Itpr1 regulates the formation of anterior eye segment tissues derived from neural crest cells,
Development, 148, dev188755, 2021, PMID: 34338282. - Sumiyoshi R, Koga T, Furukawa K, Umeda M, Yamamoto K, Mori R, Kawakami A.
A case of tocilizumab-refractory idiopathic multicentric Castleman's disease successfully treated with sirolimus.
Clinical Immunology, 233, 108887, 2021, PMID: 34798240.
2020年
- Kim SE, Mori R, Shimokawa I.
Does calorie restriction modulate inflammaging via FoxO transcription factors?
Nutrients, 12, 1959, 2020, PMID: 32630045. - Park S, Nayantai E, Komatsu T, Hayashi H, Mori R, Shimokawa I.
NPY deficiency prevents postmenopausal adiposity by augmenting estradiol-mediated browning.
Journals of Gerontology series a, 75, 1042-1049, 2020, PMID: 30561530. - Wang Z, Komatsu T, Ohata Y, Watanabe Y, Yuan Y, Yoshii Y, Park S, Mori R, Satou M, Kondo Y, Shimokawa I, Chiba T.
Effects of rikkunshito supplementation on resistance to oxidative stress and lifespan in mice.
Geriatrics and Gerontology International, 20, 238-247, 2020, PMID: 31855319.
2019年
- Komatsu T, Park S, Hayashi H, Mori R, Yamaza H, Shimokawa I.
Mechanisms of Calorie Restriction: A Review of Genes Required for the Life-extending and Tumor-inhibiting Effects of Calorie Restriction,
Nutrients, 11, 3068, 2019, PMID: 31888201. - Umehara T, Mori R, Mace KA, Murase T, Abe Y, Yamamoto T, Ikematsu K.
Identification of specific microRNAs in neutrophils of type 2 diabetic mice: overexpression of microRNA-129-2-3p accelerates diabetic wound healing.
Diabetes, 68, 617-630, 2019, PMID: 30523028.
2018年
- de Kerckhove M, Tanaka K, Umehara T, Okamoto M, Kanematsu S, Hayashi H, Yano H, Nishiura S, Tooyama S, Matsubayashi Y, Komatsu T, Park S, Okada Y, Takahashi R, Kawano Y, Hanawa T, Iwasaki K, Nozaki T, Torigoe H, Ikematsu K, Suzuki Y, Tanaka K, Martin P, Shimokawa I, Mori R.
Targeting miR-223 in neutrophils enhances the clearance of Staphylococcus aureus in infected wounds,
EMBO Molecular Medicine, 10, e9024, 2018, PMID: 30171089.
本論文は EMBO Molecular Medicine の News & Views で紹介されました。
https://www.embopress.org/doi/full/10.15252/emmm.201809574
- Mori R, Tanaka K，Shimokawa I.
Identification and functional analysis of inflammation-related miRNAs in skin wound repair,
Development Growth & Differentiation, 60, 306-315, 2018, PMID: 29873073.
2017年
- Tanaka K, Kim SE, Yano H, Matsumoto G, Ohuchida R, Ishikura Y, Araki M, Araki K, Park S, Komatsu T, Hayashi H, Ikematsu K, Tanaka K, Hirano A, Martin P, Shimokawa I, Mori R.
MiR-142 is required for Staphylococcus aureus clearance at skin wound sites via small GTPase-mediated regulation of the neutrophil actin cytoskeleton,
Journal of Investigative Dermatology, 137, 931-940, 2017, PMID: 27894934. - Park S, Komatsu T, Kim SE, Tanaka K, Hayashi H, Mori R, Shimokawa I.
Neuropeptide Y resists excess loss of fat by lipolysis in calorie-restricted mice: a trait potential for the life-extending effect of calorie restriction,
Aging Cell, 16, 339-348, 2017, PMID: 28101970. - Park S, Mori R, Shimokawa I.
The fat regulator neuropeptide Y and caloric restriction,
Aging (Albany NY), 9, 2243-2244, 2017, PMID: 29207376.
2016年
- Pei W, Tanaka K, Huang SC, Xu L, Liu B, Sinclair J, Idol J, Varshney GK, Huang H, Lin S, Nussenblatt RB, Mori R, Burgess SM.
Extracellular HSP60 triggers tissue regeneration and wound healing by regulating inflammation and cell proliferation,
npj Regenerative Medicine, 1, 16013, 2016, PMID: 28936359. - Doi H, Kitajima Y, Luo L, Yan C, Tateishi S, Ono Y, Urata Y, Goto S, Mori R, Masuzaki H, Shimokawa I, Hirano A, Li TS.
Potency of umbilical cord blood- and Wharton’s jelly-derived mesenchymal stem cells for scarless wound healing,
Scientific Reports, 6, 18844, 2016, PMID: 26728342.
2015年
- Nunan R, Campbell J, Mori R, Pitulescu ME, Jiang WG, Harding KG, Adams RH, Nobes CD, Martin P.
Ephrin-Bs drive junctional downregulation and actin stress fiber disassembly to enable wound re-epithelialization,
Cell Reports, 13, 1380-1395, 2015, PMID: 26549443. - Kim SE, Mori R, Komatsu T, Chiba T, Hayashi H, Park S, Sugawa MD, Dencher NA, Shimokawa I.
Upregulation of cytochrome c oxidase subunit 6b1 (Cox6b1) and formation of mitochondrial supercomplexes: implication of Cox6b1 in the effect of calorie restriction,
Age (Dordr), 37, 9787 ,2015, PMID: 25929654. - Shimokawa I, Komatsu T, Hayashi N, Kim SE, Kawata T, Park S, Hayashi H, Yamaza H, Chiba T, Mori R.
The life-extending effect of dietary restriction requires Foxo3 in mice,
Aging Cell, 14, 707-709, 2015, PMID: 25808402. - Kamohara R, Yamaza H, Tsuchiya T, Komatsu T, Park S, Hayashi H, Chiba T, Mori R, Otabe S, Yamada K, Nagayasu T, Shimokawa I.
Overexpression of the adiponectin gene mimics the metabolic and stress resistance effects of calorie restriction, but not the anti-tumor effect,
Experimental Gerontology, 64, 46-54, 2015, PMID: 25698374.
2014年
- Mori R, Tanaka K, de Kerckhove M, Okamoto M, Kashiyama K, Tanaka K, Kim SE, Kawata T, Komatsu T, Park S, Ikematsu K, Hirano A, Martin P, Shimokawa I.
Reduced FOXO1 accelerates skin wound healing and attenuates scarring.
American Journal of Pathology, 184, 2465-2479, 2014, PMID: 25010393. - Chiba T, Tamashiro Y, Park D, Kusudo T, Fujie R, Komatsu T, Kim SE, Park S, Hayashi H, Mori R, Yamashita H, Chung HY, Shimokawa I.
A key role for neuropeptide Y in lifespan extension and cancer suppression via dietary restriction,
Scientific Reports, 4, 4517, 2014, PMID: 24682105. - Park S, Fujishita C, Komatsu T, Kim SE, Chiba T, Mori R, Shimokawa I.
NPY antagonism reduces adiposity and attenuates age-related imbalance of adipose tissue metabolism,
FASEB Journal, 28, 5337-5348, 2014, PMID: 25205743.
2013年
- Park S, Mori R, Shimokawa I.
Do sirtuins promote mammalian longevity?: A Critical review on its relevance to the longevity effect induced by calorie restriction.
Molecules and Cells, 35, 474-480, 2013, PMID: 23661364.
2012年
- Chiba T, Tsuchiya T, Mori R, Shimokawa I.
Protein reporter bioassay systems for the phenotypic screening of candidate drugs: a mouse platform for anti-aging drug screening.
Sensors (Basel), 12, 1648-1656, 2012, PMID: 22438730.
2011年
- Mori R, Ikematsu K, Kitaguchi T, Kim SE, Okamoto M, Chiba T, Miyawaki A, Shimokawa I, Tsuboi T.
Release of tumor necrosis factor-alpha from macrophages is mediated by small GTPase Rab37. European Journal of Immunology, 41, 3230-3239, 2011, PMID: 21805469. - Komatsu T, Trindade LS, Chiba T, Hayashi H, Henmi T, Ushiroda Y, Mori R, Shimokawa I.
Acute stress response modified by modest inhibition of growth hormone axis: a potential machinery of the anti-aging effect of calorie restriction,
Mechanisms of Ageing and Development, 132, 103-109, 2011, PMID: 21291903.
2010年
- Shaw TJ, Kishi K, Mori R.
Wound-associated skin fibrosis: mechanisms and treatments based on modulating the inflammatory response.
Endocrine Metabolic & Immune Disorders-Drug Targets, 10, 320-330, 2010, PMID: 20923404. - Chiba T, Tsuchiya T, Komatsu T, Mori R, Hayashi H, Shimokawa I
Development of calorie restriction mimetics as therapeutics for obesity, diabetes, inflammatory and neurodegenerative diseases,
Current Genomics, 11, 562-567, 2010, PMID: 21629433. - Chiba T, Tsuchiya T, Komatsu T, Mori R,Hayashi H, Shimano H, Spindler SR, Shimokawa I.
Development of a bioassay to screen for chemicals mimicking the anti-aging effects of calorie restriction,
Biochemical and Biophysical Research Communications, 401, 213-218, 2010, PMID: 20846506. - Yamaza H, Komatsu T, Wakita S, Kijogi C, Park S, Hayashi H, Chiba T, Mori R, Furuyama T, Mori N, Shimokawa I.
FoxO1 is involved in the antineoplastic effect of calorie restriction,
Aging Cell, 9, 372-382, 2010, PMID: 20222901.
2008年
- Mori R, Shaw TJ, Martin P.
Molecular mechanisms linking wound inflammation and fibrosis: acute knockdown of osteopontin leads to rapid repair and reduced scarring,
Journal of Experimental Medicine, 205, 43-51, 2008, PMID: 18180311.
（下記文章は研究でもリンクしていただいております）
本研究成果はメディア（BBC News, http://news.bbc.co.uk/2/hi/health/7199897.stm ）、
他の学術専門誌に紹介されました（Nat Med, https://doi.org/10.1038/nm0308-252 ） - Anderson AA, Ushakov DS, Ferenczi MA, Mori R, Martin P, Saffell JL.
Morphoregulation by acetylcholinesterase in fibroblasts and astrocytes,
Journal of Cellular Physiology, 215, 82-100, 2008, PMID: 17948252.
2007年
- Stramer BM, Mori R, Martin P.
The inflammation-fibrosis link? A Jekyll and Hyde role for blood cells during wound repair.
Journal of Investigative Dermatology, 127, 1009-1017, 2007, PMID: 17435786.
2006年
- Mori R, Power KT, Wang CM, Martin P, Becker DL.
Acute downregulation of connexin43 at wound sites leads to a reduced inflammatory response, enhanced keratinocyte proliferation and wound fibroblast migration,
Journal of Cell Science, 119, 5193-5203, 2006, PMID: 17158921.
2004年
- Mori R, Kondo T, Nishie T, Ohshima T, Asano M.
Impairment of skin wound healing in beta-1,4-galactosyltransferase-deficient mice with reduced leukocyte recruitment,
American Journal of Pathology, 164, 1303-1314, 2004, PMID: 15039218.
2002年
- Mori R, Kondo T, Ohshima T, Ishida Y, Mukaida N.
Accelerated wound healing in tumor necrosis factor receptor p55-deficient mice with reduced leukocyte infiltration,
FASEB Journal, 16, 963-974, 2002, PMID: 12087057. - Kondo T, Tanaka J, Ishida Y, Mori R, Takayasu T, Ohshima T.
Ubiquitin expression in skin wounds and its application to forensic wound age determination,
International Journal of Legal Medicine, 116, 267-272, 2002, PMID: 12376835. - Kondo T, Ohshima T, Mori R, Guan DW, Ohshima K, Eisenmenger W.
Immunohistochemical detection of chemokines in human skin wounds and its application to wound age determination.
International Journal of Legal Medicine, 116, 87-91, 2002, PMID: 12056526.
2001年
- Higashitani K, Kondo T, Sato Y, Takayasu T, Mori R, Ohshima T.
Complete transection of the pancreas due to a single stamping injury: a case report.
International Journal of Legal Medicine, 115, 72-75, 2001, PMID: 11724433.
2000年
- Takao N, Mori R, Kato H, Shinohara A, Yamamoto K.
c-Abl tyrosine kinase is not essential for ataxia telangiectasia mutated functions in chromosomal maintenance.
Journal of Biological Chemistry, 275, 725-728, 2000, PMID: 10625600.
1999年
- Takao N, Kato H, Mori R, Morrison C, Sonoda E, Sun X, Shimizu H, Yoshioka K, Takeda S, Yamamoto KI.
Disruption of ATM in p53-null cells causes multiple functional abnormalities in cellular response to ionizing radiation,
Oncogene, 18, 7002-7009, 1999, PMID: 10597300.
