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| DNA damage and ATM kinase activation: Multiple phosphorylation sites |
Sergei V Kozlov, Ph. D.
Radiation Biology and Oncology Laboratory,
The Queensland Institute of Medical Research, Brisbane, Australia |
| ATM protein is involved in multiple aspects of cellular metabolism, such as response to genotoxic stress, proliferation, and maintaining genetic stability. ATM is a protein kinase which is rapidly activated in the presence of DNA double strand breaks, but the mechanism of ATM kinase activation remains poorly understood. In this seminar, a role of multiple phosphorylation sites will be dicussed. |
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