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The 17th Seminar

iPS cell research, current situation and challenges

Dr. Takashi Aoi
Institute for Frontier Medical Sciences, Kyoto University


In the process to establish the pluripotent stem cell for truly practical clinical trial, iPS (induced Pluripotent Stem cell) has been established. iPS cell research have been progressing very rapidly from the 2006 in which mouse iPS cell had been established, through the 2007 in which human iPS cell established, to the present. Would the iPS cell become the same as ES (embryonic stem) cell? What is the mechanism to induce the pluripotency? Can we use the iPS cell established from various patients to study the pathogenesis of the disease, or to develop the treatment or to apply the drug discovery? I will introduce the knowledge acquired over the last few years and will discuss the possibilities, direction and challenges of the iPS cell research.
 
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